|  | 1538 Cortes conquers Mexico 1547 Ivan the Terrible rules Russia 1558 Elizabeth I is England's queen 1580 Drake completes voyage around world 1582 New Gregorian calendar introduced | 1492 Columbus discovers West Indies 1498 Vasco da Gama sails to India 1503 Leonard da Vinci paints Mona Lisa 1512 Michelangelo paints Sistine Chapel 1534 Henry VIII controls English church | 1434 Medici rules in Florence 1440 Gutenberg, printing w/type 1453 End of Hundred Years War 1479 Formation of kingdom of Spain 1488 Diaz rounds Cape of Good Hope | 
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|  |  | John Egerton b.1453 Wrinehill, Staffs. d.1518 | ||||||
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|  | Isabel Egerton b.1496 Wrinehill, Staffs. d. |  |  |  |  | Ralph Brereton b.1434 Brereton, Cheshire d. |  | |
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|  |  |  | Randle Brereton b.1452 Cheshire. d. |  | Catherine Bulkeley b. Brereton, Cheshire. d. |  | ||
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|  |  | Eleanor Brereton b.1476 Ipsones, Cheshire. d.1567 | ||||||
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|  |  |  | Emma Carrington b.1457 Carrington, Cheshire. d. | |||||
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